Dr Chima Ahanotu:
I glanced through this article initially and IGNORED IT! Because I read such EVERYDAY! However when you called my name, I went back to read it well, so that I can respond as follows:
1. It is true (as Dr Fauci was quoted to be saying) that the clinical community needs more dependable antibiotics because several common disease-causing bacteria are developing resistance against the available antibiotics.
2. There are NUMEROUS anti-microbial agents (anti-bacterial, anti-viral, anti-fungal etc) identified EVERYDAY in plants, fish, snails, insects etc, such as the chemicals found in roaches by these British group; however, the efficacies and toxicity levels may not be acceptable for human use; so these potential anti-microbials NEVER MAKE THEIR WAYS into the clinic to treat human diseases.
3. If you have ever seen a laboratory agar plate containing "dots" of bacterial colonies, realize that each of those colonies may contain millions to billions of single bacteria. So if you have a chemical that can kill only about 90 percent of bacteria, realize that if a colony has about one million bacteria, 100,000 of the bacteria (which is 10 percent of 1,000,000) will be left alive after the chemical acts against the growing bacteria. That 10 percent can cause SERIOUS PROBLEMS unless you keep using it again and again and again! And this is how antibiotic RESISTANCE develops; the genetic plasticity of the bacterial genomes allows for the development and selection of mutant strains that are longer susceptible to the chemical; this is the basis of antibiotic resistance!
Take care. JUI
From: NaijaPolitics@yahoogroups.com [mailto:NaijaPolitics@yahoogroups.com] On Behalf Of Chim Ahanotu
Sent: Tuesday, September 07, 2010 5:43 PM
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Subject: [NaijaPolitics] Cockroaches: The Antibiotics of the Future?
Ok, Dr. Igietseme, is it ok now to eat roaches or what? Hmmmmmmmmmm. let's see
what the Chinese will come up with their own version of herb mixture with
roaches.
________________________________
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Sent: Tue, September 7, 2010 3:56:10 PM
Subject: [NaijaPolitics] (no subject)
Cockroaches: The Antibiotics of the Future?
Updated: 1 hour 54 minutes ago
Print Text Size
Katie Drummond ContributorAOL News Surge Desk
(Sept. 7) -- Cockroaches, the creepy critters reviled for invading kitchens the
country over, might be modern medicine's best option for fending off dangerous,
drug-resistant bacterial infections.
British researchers at the University of Nottingham's School of Veterinary
Medicine and Science are behind the discovery, which entails harnessing
molecules from the tissues of cockroaches and locusts to combat bacteria like E.
coli and MRSA (drug-resistant staph infections).
Sakchai Lalit, AP
Chemicals found in the brain and central nervous tissues of cockroaches are able
to kill 90 percent of dangerous bacteria in lab-based tests.
The potent chemicals, found in the brain and central nervous tissues of the
critters, are able to kill 90 percent of E. coli and MRSA in lab-based tests.
"Superbugs ... have shown the ability to cause untreatable infections and have
become a major threat in our fight against bacterial diseases," Dr. Naveed Khan,
who supervised the work of lead researcher Simon Lee, said in a press release.
"Thus, there is a continuous need to find additional sources of novel
anti-microbials to confront this menace."
In a twist that's an ironic upside to our own revulsion for roaches, it's their
"unsanitary and unhygienic environments," Lee speculated, that spurred the
critters to develop toxins against the bacteria.
Sponsored Links After this initial success, the same U.K. team is testing the
cockroach-derived toxins against other harmful "superbugs" that are increasingly
resistant to existing pharmaceuticals. Indeed, the finding comes as the need for
new anti-microbials is increasing. Health experts continue to warn that
bacterial infections will soon be entirely resistant to current modes of
treatment.
"This community, by and large, lacks the resources to move a candidate
antimicrobial drug all the way from preclinical testing through advanced
development," Anthony Fauci, director of the National Institute of Allergy and
Infectious Diseases, said in April. "We desperately need to develop new classes
of drugs to ensure that we have viable treatment options."
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